GM-CSF at relatively high topic concentrations can significantly enhance the healing of surgically induced chronic wounds after radiotherapy

Authors
Fernberg, JO Brosjo, O Friesland, S Masucci, G
Citation
Jo. Fernberg et al., GM-CSF at relatively high topic concentrations can significantly enhance the healing of surgically induced chronic wounds after radiotherapy, MED ONCOL, 18(3), 2001, pp. 231-235
Citations number
10
Categorie Soggetti
Oncology
Journal title
MEDICAL ONCOLOGY
ISSN journal
13570560 → ACNP
Volume
18
Issue
3
Year of publication
2001
Pages
231 - 235
Database
ISI
SICI code
1357-0560(2001)18:3<231:GARHTC>2.0.ZU;2-8
Abstract
Combinations of radiotherapy and surgery are often used in local cancer tre atments. Preoperative radiotherapy may delay wound healing after surgery. Chronic wounds are debilitating conditions that require frequent medical at tention. Two patients suffering from chronic and slowly healing wounds post -surgery and preoperative radiotherapy are described. A significant acceler ation of the healing by local injections with GM-CSF was demonstrated.