Aims of diagnosing addiction comprise the assessment of the dependence
syndrome including development severity and negative consequences in
particular patients, of comorbidity and relapse events when patients a
re referred for treatment, Data of our own studies indicate that the d
ependence syndrome develops earlier and more pronounced in opiate addi
cts compared to alcoholics. In female alcoholics the addictive process
starts 4-7 years later than in males which is supposed to be mainly d
ue to psychosocial factors that incriminate excessive drinking of fema
les in the public domain. Compared to pure alcoholics antisocial perso
nality trails have some accelerating, anxious and depressive symptoms
some decelerating effects on the progression of alcoholism Diagnostic
efforts of the clinician can be supported by determining CDT in serum
that is a useful indicator of heavy alcohol consumption ard - as recen
tly shown by own data - of relapse.