Retrieval of long and short lists from long term memory: a functional magnetic resonance imaging study with human subjects

Previous studies have shown that reaction time in an item-recognition task with both short and long lists is a quadratic function of list length. This suggests that either different memory retrieval processes are implied for short and long lists or an adaptive process is involved. An event-related f unctional magnetic resonance imaging study with nine subjects and list leng ths varying between 3 and 18 words was conducted to identify the underlying neuronal structures of retrieval from long and short lists. For the retrie val and processing of word-lists a single fronto-parietal network, includin g premotor, left prefrontal, left precuneal and left parietal regions, was activated. With increasing list length, no additional regions became involv ed in retrieving information from long-term memory, suggesting that not nec essarily different, but highly adaptive retrieval processes are involved. ( C) 2001 Elsevier Science Ireland Ltd. All rights reserved.