Thiacalix[4] tube: synthesis, X-ray crystal structure and preliminary binding studies

Authors
Matthews, SE Felix, V Drew, MGB Beer, PD
Citation
Se. Matthews et al., Thiacalix[4] tube: synthesis, X-ray crystal structure and preliminary binding studies, NEW J CHEM, 25(11), 2001, pp. 1355-1358
Citations number
17
Categorie Soggetti
Chemistry
Journal title
NEW JOURNAL OF CHEMISTRY
ISSN journal
11440546 → ACNP
Volume
25
Issue
11
Year of publication
2001
Pages
1355 - 1358
Database
ISI
SICI code
1144-0546(2001)25:11<1355:TTSXCS>2.0.ZU;2-5
Abstract
The calix [4] tube family of ionophores has been extended to encompass the slightly larger thiacalix [4] tube. H-1 NMR and crystallographic studies sh ow the ligand to adopt a flexible C-2v flattened cone arrangement. However, in contrast to the parent calix [4] tube, preliminary binding studies show no selectivity for potassium, in agreement with the absence of a template effect in tube formation and molecular modelling studies.