OBJECTIVE: To apply urine-based ligase chain reaction for Chlamydia trachom
atis (C trachomatis) and Neisseria gonorrhoeae (N. gonorrhoeae) detection a
nd standard urine-based pregnancy testing for Navy-enlisted women, and to c
ompare the prevalence and epidemiologic correlates of these adverse reprodu
ctive outcomes.
METHODS: Participants were surveyed and urine was collected for pregnancy t
esting using standard laboratory methods and detection of C trachomatis and
N. gonorrhoeae infection by ligase chain reaction. Self-administered surve
ys facilitated collection of demographics, sexual behavior, including contr
aceptive use, sexual partners, sexually transmitted disease, and pregnancy
history.
RESULTS: Among 299 of 314 participants, the prevalence of chlamydial infect
ion was 4.7% and of pregnancy was 9.7%, with 48.3% of the pregnancies unpla
nned. Chlamydia trachomatis infection was univariately associated with havi
ng a new sex partner within the last 6 months, more sexual partners, single
marital status, condom use, drinking until passing out or vomiting in the
past 30 days (alcohol misuse), and current pregnancy. Unplanned pregnancy w
as univariately associated with young age, single marital status, inconsist
ent condom use, having a new sex partner within the last 6 months, and more
recent sexual partners. Among the pregnant women, four (13.8%) were infect
ed with C trachomatis.
CONCLUSION: The high rates of chlamydial infection and unplanned pregnancy
found in this population of employed young women with ready access to healt
h care and health education underscore the challenge of enhancing reproduct
ive health via compliance with effective contraceptive and sexually transmi
tted disease prevention methods. This is a challenge that remains unmet. (O
bstet Gynecol 2001;98:1117-23. (C) 2001 by the American College of Obstetri
cians and Gynecologists.).