Gestational trophoblastic disease

The pathophysiology of the spectrum of conditions that constitute gestation al trophoblastic disease is discussed in this article. Current modalities a vailable for the diagnosis of these conditions are reviewed. The staging of gestational trophoblastic neoplasia is also reviewed with particular empha sis on prognostic factors that influence treatment decisions. Finally, curr ent trends in the management of trophoblastic tumors and the overall progno sis for these patients are addressed in the article.