N,N '-Di-tert-butoxycarbonyl-1H-benzotriazole-1-carboxamidine derivatives are highly reactive guanidinylating reagents

Authors
Musiol, HJ Moroder, L
Citation
Hj. Musiol et L. Moroder, N,N '-Di-tert-butoxycarbonyl-1H-benzotriazole-1-carboxamidine derivatives are highly reactive guanidinylating reagents, ORG LETT, 3(24), 2001, pp. 3859-3861
Citations number
24
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
24
Year of publication
2001
Pages
3859 - 3861
Database
ISI
SICI code
1523-7060(20011129)3:24<3859:N'DA>2.0.ZU;2-X
Abstract
[GRAPHICS] By enhancing the leaving group character of benzotriazole via electron-with drawing substituents such as the 5-chloro or 6-nitro derivatives with the r elated N,N'-di-tert butoxycarbonyl-1H-benzotriazole-1-carboxamidines, highl y efficient reagents are obtained for conversion of primary and secondary a mines in solution and in solid phase to diprotected guanidines.