PECULIARITIES OF CLINICAL COURSE OF NEPHR ITIS IN PATIENTS WITH CRYOGLOBULINEMIA

Citation
Nb. Gordovskaya et al., PECULIARITIES OF CLINICAL COURSE OF NEPHR ITIS IN PATIENTS WITH CRYOGLOBULINEMIA, Terapevticeskij arhiv, 69(6), 1997, pp. 30-34
Citations number
32
Categorie Soggetti
Medicine, General & Internal
Journal title
ISSN journal
00403660
Volume
69
Issue
6
Year of publication
1997
Pages
30 - 34
Database
ISI
SICI code
0040-3660(1997)69:6<30:POCCON>2.0.ZU;2-D
Abstract
Cryoglobulins were measured spectrophotometrically in the sera of 40 p atients with renal diseases. 18 of them had chronic glomerulonephritis , 14 lupus nephritis and 8 nephritis. 20 patients with high concentrat ion of cryoglobulins (100-600 mu g/ml) exhibited high incidence of nep hrotic syndrome (80%), arterial hypertension (90%), creatininemia (70% ) and, respectively, 25, 25 and 15% of patients free of cryoglobulinem ia. There was a correlation between cryoglobulins level and creatinine mia (r = 0.468), proteinuria (r = 0.478), ESR (r = 0,393), systolic an d dyastolic arterial pressure (r = 0.393 and r = 342, respectively). A n inverse relation existed with serum albumins (r = -0.526). Progressi on of renal failure was associated with high cryoglobulinemia. In decl ine of cryoglobulins content there was clinical improvement, lowering or normalization of blood creatinin levels.