The most general one dimensional reaction-diffusion model with nearest-neig
hbor interactions that can be solved exactly through empty-interval method
has been introduced. Assuming translationally invariant initial conditions.
the probability that n consecutive sites are empty, E-n, has been exactly
obtained. Here, however. we do not consider reactions changing two empty ne
ighboring sites. In the thermodynamic limit, the large-time behavior of the
system has also been investigated. Releasing translationally invariance, t
he evolution equation for the probability that n consecutive sites. startin
g from the site k, are empty, E-k,E-n, is obtained. In the thermodynamic li
mit. the large time behavior of the system is also considered. Finally, the
continuum limit of the model is considered and the empty-interval probabil
ity function is obtained.