P. Znidarsic et al., Studies on supporting media for progesterone 11 alpha-hydroxylation with apelleted growth form of Rhizopus nigricans, ACTA CHIM S, 48(4), 2001, pp. 533-544
Studies on supporting medium composition and its feed rate were performed i
n order to maintain stationary biomass concentration during the process of
progesterone hydroxylation with Rhizopus nigricans pellets. Growth kinetic
parameters were evaluated for two media with different nitrogen sources. Th
e results indicate the benefit of using complex media at higher feed rates
than those used for the maintenance of stationary biomass concentration wit
hout exogenous steroid addition.