Although, one out of every eight women has a risk of developing breast canc
er. the reported incidence of breast carcinoma detection in reduction mamma
plasty materials is rather low. To our knowledge, specimen radiography, whi
ch is used for breast biopsies has not been used for the assessment of brea
st reduction materials. We investigated the applicability of specimen radio
graphy and its potential benefits in detection of the breast pathologies, e
specially malignancies in reduction mammaplasty materials. Forty patients s
cheduled for reduction mammaplasty operation were included. In all cases an
inferior pedicle reduction technique was preferred and the radiographs of
the resected breast tissues were taken immediately. The radiographs were ev
aluated for any possible pathologic appearance and all abnormal findings we
re marked. For the histopathologic evaluation, in addition to the random sa
mpling of the pathologist, any marked areas were also microscopically exami
ned. In two cases fibrocystic changes were found in radiographs and the sam
e results were obtained in the histological examination. No false negative
mammogram was seen. Specimen radiography. which is applicable for breast re
duction materials is an easy and cheap method and does not cause any patien
t discomfort. It seems that the radiographs of reduction mammaplasty materi
als are useful to provide guidance to the pathologist during tissue samplin
g for microscopic examination especially when large a-mounts of breast tiss
ue is excised.