Modeling of the separation of the enantiomers of 1-phenyl-1-propanol on cellulose tribenzoate

The competitive adsorption isotherms of rac-1-phenyl-1-propanol on cellulos e tribenzoate were measured by competitive frontal analysis. The experiment al data were fitted to four different isotherm models: Langmuir, Bi-langmui r, Langmuir-Freundlich, and Toth. The fittings of the experimental data to all four models were satisfactory. It was excellent in the case of the Lang muir-Freundlich and the Toth models. Overloaded elution profiles calculated with the Toth isotherm were in good agreement with the experimental profil es in all the different experimental conditions investigated. This work ext ends to the case of binary mixtures the equivalence between the general rat e and the lumped pore diffusion models already demonstrated for pure compou nds when the ratio between the Stanton and the Biot numbers exceeds 5. The adsorption energy distribution for the Toth isotherm was also calculated.