Association of CD4(+)/CD56(+)/CD57(+)/CD8(+dim) large granular lymphocyticleukemia, splenic B-cell lymphoma with circulating villous lymphocytes, and idiopathic erythrocytosis

Authors
Lima, M Goncalves, C Marques, L Martin, MD Teixeira, MD Queiros, ML Santos, AH Balanzategui, A Garcia-Sanz, R Pinto-Ribeiro, AC Justica, B Orfao, A
Citation
M. Lima et al., Association of CD4(+)/CD56(+)/CD57(+)/CD8(+dim) large granular lymphocyticleukemia, splenic B-cell lymphoma with circulating villous lymphocytes, and idiopathic erythrocytosis, ANN HEMATOL, 80(11), 2001, pp. 685-690
Citations number
23
Categorie Soggetti
Hematology,"Cardiovascular & Hematology Research
Journal title
ANNALS OF HEMATOLOGY
ISSN journal
09395555 → ACNP
Volume
80
Issue
11
Year of publication
2001
Pages
685 - 690
Database
ISI
SICI code
0939-5555(200111)80:11<685:AOCLGL>2.0.ZU;2-0
Abstract
In this paper we report a rare association of a splenic marginal zone B-cel l lymphoma with villous lymphocytes and a T-cell large granular lymphocytic leukemia coexpressing CD4 and CD8 as well as CD56 and CD57 natural killer- associated markers in an asymptomatic patient investigated because of an oc casional finding of erythrocytosis and leukocytosis in routine blood analys is. We also discuss the possible reasons for this particular association.