Malaria is endemic in the Indian state of Assam and transmission of the cau
sative parasites is perennial and persistent. The available data on malaria
-related morbidity and mortality in the state for the years 1991-1999 have
been reviewed. Over this period, Plasmodium falciparum was the predominant
parasite, causing 58%-68% of the malaria cases; all other cases were attrib
uted to P. vivax. All malaria-related deaths were attributed to P. falcipar
um infection, and the numbers of such deaths were correlated with the numbe
rs of cases of P. falciparum malaria. The deaths occurred mostly in the rai
ny season (April-September) and among all age-groups of both sexes. The fac
tors responsible for focal outbreaks of malaria across the state are discus
sed in relation to the existing health infrastructure.