Factors affecting over-the-counter use of aspirin in the secondary prophylaxis of cardiovascular disease

Little is known about the contribution of over-the counter (OTC) aspirin to cardiovascular prophylaxis. To investigate this, a two-phase cross-section al study was carried out in nine general practices in North Staffordshire. In the first phase, all patients with cardiovascular disease (CVD) were ide ntified from computer searches using morbidity registers and drug searches. The search also identified the subgroup receiving prescribed prophylactic aspirin. IN the second phase, a questionnaire was posted to all patients wi th CVD who were not on prescribed aspirin to establish their current use of OTC aspirin. Overall, 69% of the CVD group used aspirin, with 26% of aspir in being OTC. OTC aspirin use was more common in those aged under 65 years, men and the more affluent. Also, there were significant differences in OTC aspirin use between the various practices. This study shows that a conside rable amount of aspirin is used OTC in those with CVD. Its use is influence d by several factors that could be addressed when considering attempts to i mprove the overall uptake of aspirin.