Deletion 5p11 accompanied by multiple numerical changes in testicular lymphoma

We describe a case of testicular B cell lymphoma with deletion of chromosom e 5, del(5)(p11), as a sole structural abnormality. Histopathological diagn osis of the tumor was a high-grade lymphoma of the diffuse type containing cells positive for B cell specific antigen (CD20) and negative for the leuk ocyte common antigen (CD45). Deletion 5p may define the region of a tumor s uppressor gene that could be associated with tumor progression and invasive ness and may serve as an indicator of poor prognosis in testicular lymphoma s. (C) 2001 Elsevier Science Inc. All rights reserved.