Subcortical dementia associated with striking enlargement of the Virchow-Robin spaces and transneural degeneration of the left mammillo-thalamic tract

We report a case of subcortical dementia in a 68-year-old woman. MR examina tion of the patient's brain revealed two types of alterations as a possible cause of the dementia, both anomalous in respect of their entity and incid ence: the first was a striking enlargement of the Virchow-Robin spaces, and the second an anterograde transneural degeneration of the left mammillo-th alamic tract and mammillary body secondary to a lacunar infarction of the i psilateral anterior thalamus. Copyright (C) 2001 S. Karger AG, Basel.