Thrombotic occlusion of the internal cerebral veins is a particularly dange
rous form of cerebral venous thrombosis (CVT) as it causes venous infarctio
n of the thalami. Because both thalami drain into the vein of Galen and str
aight sinus, bilateral thalamic involvement is frequently encountered in in
ternal CVT. However, unilateral thalamic edema may also occur, even if all
internal cerebral veins are occluded. This suggests collateral venous drain
age of the thalami, which is commonly insufficient in internal CVT. Patient
s with unilateral congestion of the thalamus, including 3 patients reported
here, had mostly left-sided involvement, indicating that right-sided unila
teral thalamic involvement in CVT may be clinically silent. Copyright (C) 2
001 S. Karger AG, Basel.