An improved procedure for packing capillaries for capillary electrochromatography

This paper introduces a novel improvement to high pressure slurry packing o f CEC capillaries. Slurry homogeneity is maintained by constantly stirring in a 'balanced density' solvent system in a vessel with a configuration tha t prevents silica agglomerates from blocking the capillary inlet. Up to nin e, one metre length capillaries may be packed simultaneously and repeatably in under 3 hours. All capillaries produced peak efficiencies greater than 100,000 plates / metre with 5 mum Spherisorb ODS1 and showed capillary to c apillary variability of less than 10% in terms of peak symmetry and peak ef ficiency The data has been presented in part, at the 23(rd) International S ymposium in Chromatography 2000.