Chagasic meningoencephalitis in a patient with acquired immunodeficiency syndrome: Diagnosis, follow-up, and genetic characterization of Trypanosoma cruzi

Authors
Lages-Silva, E Ramirez, LE Silva-Vergara, ML Chiari, E
Citation
E. Lages-silva et al., Chagasic meningoencephalitis in a patient with acquired immunodeficiency syndrome: Diagnosis, follow-up, and genetic characterization of Trypanosoma cruzi, CLIN INF D, 34(1), 2002, pp. 118-123
Citations number
39
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
10584838 → ACNP
Volume
34
Issue
1
Year of publication
2002
Pages
118 - 123
Database
ISI
SICI code
1058-4838(20020101)34:1<118:CMIAPW>2.0.ZU;2-7
Abstract
Early diagnosis of the clinical reactivation of Chagas' disease in human im munodeficiency virus- and Trypanosoma cruzi-coinfected persons is fundament al for a good prognosis. Polymerase chain reaction rapidly and efficiently demonstrated the presence and elimination of T. cruzi in the cerebrospinal fluid of a patient with chagasic meningoencephalitis. Characterization of T . cruzi, directly and indirectly in blood and cerebrospinal fluid samples, demonstrated homogeneity of kinetoplast DNA and the presence of lineage 1 ( T. cruzi II) in both parasite populations.