LIPSIA - a new software system for the evaluation of functional magnetic resonance images of the human brain

This paper describes the non-commercial software system LIPSIA that was dev eloped for the processing of functional magnetic resonance images (fMRI) of the human brain. The analysis of fMRI data comprises various aspects inclu ding filtering, spatial transformation, statistical evaluation as well as s egmentation and visualization. In LIPSIA, particular emphasis was placed on the development of new visualization and segmentation techniques that supp ort visualizations of individual brain anatomy so that experts can assess t he exact location of activation patterns in individual brains. As the amoun t of data that must be handled is enormous, another important aspect in the development LIPSIA was the efficiency of the software implementation. Well established statistical techniques were used whenever possible, (C) 2001 E lsevier Science Ltd. All rights reserved.