Orthogonal subspace projection (OSP) approach has shown success in hyperspe
ctral image classification. Recently, the feasibility of applying OSP to mu
ltispectral image classification was also demonstrated via SPOT (Satellite
Pour l'Observation de la Terra) and Landsat (Land Satellite) images. Since
an MR (magnetic resonance) image sequence is also acquired by multiple spec
tral channels (bands), this paper presents a new application of OSP in MR i
mage classification. The idea is to model an MR image pixel in the sequence
as a linear mixture of substances (such as white matter, gray matter, cere
bral spinal fluid) of interest from which each of these substances can be c
lassified by a specific subspace projection operator followed by a desired
matched filter. The experimental results show that OSP provides a promising
alternative to existing MR image classification techniques. (C) 2001 Elsev
ier Science Ltd. All rights reserved.