Regulation of sporulation in Streptomyces coelicolor A3(2): a checkpoint multiplex?

Authors
Chater, KF
Citation
Kf. Chater, Regulation of sporulation in Streptomyces coelicolor A3(2): a checkpoint multiplex?, CURR OPIN M, 4(6), 2001, pp. 667-673
Citations number
52
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
CURRENT OPINION IN MICROBIOLOGY
ISSN journal
13695274 → ACNP
Volume
4
Issue
6
Year of publication
2001
Pages
667 - 673
Database
ISI
SICI code
1369-5274(200112)4:6<667:ROSISC>2.0.ZU;2-2
Abstract
By complementing developmental mutants of Streptomyces coelicolor A3(2), at least 15 regulatory genes for sporulation have been identified and studied at the molecular level, and some of their intracellular interactions have been characterised. Extensive interplay of the regulatory cascade with meta bolic, morphological, homeostatic and stress-related checkpoints is emergin g.