Gastrointestinal issues are a major chronic problem in 80 to 90% of childre
n with cerebral palsy and in children with neurodevelopmental disabilities
who are at special risk of developing malnutrition because of uncoordinated
swallowing, gastroesophageal reflux, and constipation. In addition to poor
linear growth, there is a decrease in muscle strength and coordination, im
paired cerebral function leading to decreased motivation and energy, Signif
icant neurodevelopmental progress can be achieved with improved nutritional
status. A multidisciplinary approach, with input from neurologists, gastro
enterologists, nurses, occupational therapists, and dieticians, can make a
major contribution to the medical wellbeing and quality of life of these ch
ildren. Different neurological diseases (eg, spinal dysraphism, syringomyel
ia, tethered cord syndromes) can give rise to gastrointestinal dysfunction
and symptoms that may need different gastrointestinal or surgical managemen
t. The introduction of new drugs, including proton pump inhibitors and inno
vative endoscopic and surgical techniques in the management of gastroesopha
geal reflux disease and constipation also may have an impact on the treatme
nt of neurologically handicapped children in the future. Curr Opin Pediatr
2001, 13:441-446 (C) 2001 Lippincott Williams & Wilkins, Inc.