S. Yamamoto et al., DEVELOPMENT OF A HIGH-RESOLUTION BETA-CAMERA FOR A DIRECT MEASUREMENTOF POSITRON DISTRIBUTION ON BRAIN SURFACE, IEEE transactions on nuclear science, 44(4), 1997, pp. 1538-1542
We, have developed and tested a high resolution beta camera for a dire
ct measurement of positron distribution on the brain surface of animal
s. The beta camera consists of a thin CaF2(Eu) scintillator, a tapered
fiber optic plate (tapered fiber) and a position sensitive photomulti
plier tube (PSPMT). The tapered fiber is the key component of the came
ra We have developed two different sizes of beta cameras. One is 20mm
diameter field of view camera for imaging brain surface of cats. The o
ther is 10mm diameter camera for that of rats. Spatial resolutions of
the beta camera for cats and rats were 0.8mm FWHM and 0.5mm FWHM, resp
ectively. We demonstrated that developed beta cameras may overcome the
limitation of the spatial resolution of positron emission tomography
(PET).