Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor

Authors
Botos, I Wu, ZB Lu, WY Wlodawer, A
Citation
I. Botos et al., Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor, FEBS LETTER, 509(1), 2001, pp. 90-94
Citations number
27
Categorie Soggetti
Biochemistry & Biophysics
Journal title
FEBS LETTERS
ISSN journal
00145793 → ACNP
Volume
509
Issue
1
Year of publication
2001
Pages
90 - 94
Database
ISI
SICI code
0014-5793(20011130)509:1<90:CSOACF>2.0.ZU;2-1
Abstract
The crystal structure of a cyclic form of a mutant of bovine pancreatic try psin inhibitor has been solved at 1.0 Angstrom resolution. The protein was synthesized by native chemical ligation and its structure is almost indisti nguishable from the previously described recombinant form of the same mutan t; however, the new loop containing the former termini became much better o rdered. (C) 2001 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.