Hodgkin's lymphoma of T-cell type: Clonal association with a CD30+cutaneous lymphoma

Authors
Kadin, ME Drews, R Samel, A Gilchrist, A Kocher, O
Citation
Me. Kadin et al., Hodgkin's lymphoma of T-cell type: Clonal association with a CD30+cutaneous lymphoma, HUMAN PATH, 32(11), 2001, pp. 1269-1272
Citations number
15
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
Journal title
HUMAN PATHOLOGY
ISSN journal
00468177 → ACNP
Volume
32
Issue
11
Year of publication
2001
Pages
1269 - 1272
Database
ISI
SICI code
0046-8177(200111)32:11<1269:HLOTTC>2.0.ZU;2-9
Abstract
The derivation of Reed-Sternberg cells in Hodgkin's lymphoma has been a sub ject of great interest. In most cases, Reed-Sternberg cells seem to be deri ved from germinal center B cells. In few sporadic cases, a T-cell origin ha s been shown. This article supports the concept of a T-cell derivation for rare cases of Hodgkin's lymphoma and provides evidence of a novel mechanism of pathogenesis from chronic inflammation in the skin. Hum PATHOL 32:1269- 1272. Copyright (C), 2001 by W.B. Saunders Company.