Prognostic factors related to cervical cancer survival in Mexican women

Objective: To identify prognostic survival factors among Mexican women with cervical cancer. Methods: A total of 378 women with cervical cancer admitt ed from 1984 to 1996 to our referral hospital were evaluated, using surviva l analysis (Kaplan-Meier and Cox proportional hazards method). We designed a symptom index which included asymptomatic conditions, severity of symptom s and comorbidity. Results: Overall 5-year survival was 66.6%. The shortest survival time was for FIGO stage IV (21.5%, P < 0.001) and adenosquamous h istologic type (53.1%, P = 0.15). The main prognostic factors were primary symptoms (RR, 2.6; 95%a CI, 1.02-6.66); systemic symptoms (RR, 3.3; 95% CI, 1.23-9.01); FIGO stage IV (RR, 5.5; 95% CI, 2.36-12.96); and oncogenic sym ptoms (prognostic comorbidity present) (RR, 2.3; 95% CI, 1.08-4.89). Conclu sions: Our findings show that clinical stage and several types of symptoms influence CC survival. This present strategy to assess morphological and cl inical characteristics may be a more accurate indicator of survival rate an d potentially an efficient indicator of new therapeutic alternatives. (C) 2 001 International Federation of Gynecology and Obstetrics. All rights reser ved.