Gas chromatographic-mass spectrometric confirmation of atractyloside in a patient poisoned with Callilepis laureola

Authors
Laurens, JB Bekker, LC Steenkamp, V Stewart, MJ
Citation
Jb. Laurens et al., Gas chromatographic-mass spectrometric confirmation of atractyloside in a patient poisoned with Callilepis laureola, J CHROMAT B, 765(2), 2001, pp. 127-133
Citations number
30
Categorie Soggetti
Chemistry & Analysis
Journal title
JOURNAL OF CHROMATOGRAPHY B
ISSN journal
13872273 → ACNP
Volume
765
Issue
2
Year of publication
2001
Pages
127 - 133
Database
ISI
SICI code
1387-2273(200112)765:2<127:GCSCOA>2.0.ZU;2-S
Abstract
The South African traditional remedy Impila (Callilepis laureola) contains the mitochondrial toxin atractyloside. The plant is sold widely and continu es to lead to fatalities in patients. We describe, for the first time, a si mple GC-MS procedure for the identification of atractyloside, which we have applied to the gastric washing from a poisoned patient and to extracts of Impila tuber. (C) 2001 Elsevier Science B.V. All rights reserved.