Differences in clinical and laboratory diagnostic characteristics of penicilliosis marneffei in human immunodeficiency virus (HIV)- and non-HIV-infected patients

We compared the clinical and laboratory features of human immunodeficiency virus (HIV)- and non-HIV-infected patients with penicilliosis marneffei. HI V-infected patients had a higher incidence of fungemia. A total of 85.7% of the HIN-negative patients had underlying diseases including hematologic ma lignancies or had received therapy with corticosteroids or cytotoxic agents . By a Penicillium marneffei-specific mannoprotein Mp1p enzyme-linked immun osorbent assay, serum antigen titers were found to be higher in HIV-positiv e patients, whereas serum antibody levels were found to be higher in HIV-ne gative patients.