The purpose of this study was to identify patients with substance-use disor
ders who deteriorate during treatment, and to examine baseline predictors o
f deterioration. Three groups of 872 patients each, matched on number of pr
oblems at baseline, were selected from a larger sample based on their treat
ment outcome (improved, nonresponsive, deteriorated). Deterioration was pre
dicted by younger age and African-American race; four aspects of patients'
history (psychiatric symptoms, arrests, prior drug treatment, and recent in
patient or residential care); and having no close friends. Patients who had
both an alcohol and a drug diagnosis, a personality-disorder diagnosis, an
d those who had a shorter episode of care and fewer outpatient-mental-healt
h visits, also were more likely to deteriorate. (C) 2001 John Wiley & Sons,
Inc.