Jp. Camilleri et al., Serum soluble interleukin 2 receptor levels and radiological progression in early rheumatoid arthritis, J RHEUMATOL, 28(12), 2001, pp. 2576-2578
Objective. To investigate the association between serum soluble interleukin
2 receptor (sIL-2R) levels and radiological changes in patients with early
rheumatoid arthritis (RA).
Methods. sIL-2R levels from 155 patients with active RA were measured by im
munoassay over a 2 year period and the associations with radiological chang
e and other measures of disease activity were analyzed.
Results. The area under the curve for sIL-2R is weakly associated with the
change in the modified Larsen score over a 2 year period; this is weaker th
an the association of radiological change with serum C-reactive protein.
Conclusion. We found no significant association of sIL-2R levels with erosi
ve change in early RA.