Transient eruptive seborrheic keratoses associated with erythrodermic psoriasis and erythrodermic drug eruption: Report of two cases

Citation
Sl. Flugman et al., Transient eruptive seborrheic keratoses associated with erythrodermic psoriasis and erythrodermic drug eruption: Report of two cases, J AM ACAD D, 45(6), 2001, pp. S212-S214
Citations number
10
Categorie Soggetti
Dermatology,"da verificare
Journal title
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
ISSN journal
01909622 → ACNP
Volume
45
Issue
6
Year of publication
2001
Supplement
S
Pages
S212 - S214
Database
ISI
SICI code
0190-9622(200112)45:6<S212:TESKAW>2.0.ZU;2-2
Abstract
Tbe appearance of multiple seborrbeic keratoses in association With underly ing internal malignancy (known as the sign of Leser-Trelat) has generated m uch discussion and debate in the literature. However, comparatively,few, ca se reports exist that examine the appearance of multiple seborrheic keratos es associated with exfoliative erythroderma without underlying malignancy. We repoly 2 cases it which multiple, biopsy-proven seborrheic keratoses app eared in conjunction with erythrodermic skin eruptions. The underlying dise ases in these 2 patients included psoriasis and an eczematous drug eruption : in both cases the erythroderma resolved with appropriate treatment. After resolution of the erythroderma. the newly, developed seborrbeic keratoses proceeded to involute and gradually, fall off. Neither of the patients exhi bited any, evidence of, internal malignancy. These cases represent the firs t reports of psoriasis and drug eruption as causes of erythroderma-induced transient eruptive seborrbeic keratoses. Clinical and pathologic findings a re consistent with previous descriptions of this entity.