RADIATION-DAMAGE TO LYMPHOCYTE MEMBRANES .2. STRUCTURAL-CHANGES OF LIPID DOMAIN AFTER LOW-DOSES OF HIGH-LET IRRADIATION

The changdes of some physical parameters of lymphocyte membranes follo wing neutron irradiation from a Cf-252 source in vitro in range of ver y low doses were studied. We aimed our attention at fluorescence inten sity, fluorescence polarisation, microviscosity and order parameter of lipid bilayer of lymphocyte membranes. The values of above mentioned parameters were obtained by means of fluorescent spectrometry using 1, 6-diphenyl-1,3,5-hexatriene (DPH) as a fluorescent probe. It wits show n,that with increasing doses of radiation the values of all studied pa rameters have been decreasing. The microviscosity of membranes decreas ed to 37% of the control value.