OCULAR AND SINUS MICROSPORIDIAL INFECTION CURED WITH SYSTEMIC ALBENDAZOLE

PURPOSE: To report treatment of a patient with acquired immunodeficien cy syndrome (AIDS) and ocular and paranasal sinus microsporidial infec tion. METHOD: Case report. RESULTS: A patient with AIDS and ocular mic rosporidial infection experienced resolution of ocular symptoms with t opical fumagillin, but symptoms recurred upon cessation of therapy. Pa ranasal sinus microsporidial infection was diagnosed. The patient rece ived sequential systemic treatment with itraconazole followed by alben dazole. Sinus symptoms resolved with albendazole, He remained symptom- free with a normal examination 17 months after concluding therapy. CON CLUSIONS: Although fumagillin and itraconazole may have played a role, systemic albendazole appears to be responsible for clinical resolutio n of microsporidial infection.