[2,2]paracyclophane-based N,O-ligands in alkenylzinc additions to aldehydes

[GRAPHICS] The application of planar and central chiral [2,2]paracyclophane-based N,O- ligands in asymmetric alkenylzinc additions to various aldehydes is describ ed, which gives rise to very high ee's especially for difficult substrates. A fine-tuning of the alkenylzinc species by employing different transmetal ation reagents is reported, allowing control of the steric bulk of the alke nylzinc species and thus the selectivity of the catalysis.