Minimally invasive application of botulinum toxin type A in nasal hypersecretion

We report on the effect of the local application of botulinum toxin A on na sal hypersecretion in a female patient with intrinsic rhinitis. 20 units of botulinum toxin A (Botox (R)) was inserted into each nostril using a small sponge in close contact with the lower and middle turbinates. The effect w as scored by the patient and by rhinomanometry. Nasal hypersecretion dimini shed clearly 5 days after the treatment. The rhinomanometric flow increased 2 weeks after the application. No side effects occurred. We conclude that this minimal invasive method of local botulinum toxin application might be a very effective and safe option for the treatment of nasal hypersecretion of different etiologies. Copyright (C) 2001 S. Karger AG, Basel.