A. Pomeranz et al., Eosinophilic cystitis in a 4-year-old boy: Successful long-term treatment with cyclosporin A, PEDIATRICS, 108(6), 2001, pp. NIL_90-NIL_93
A 4-year-old Jewish boy presented with dysuria, urinary dribbling, increase
d urinary frequency, and new onset of diurnal enuresis. An infiltrating sol
id mass involving the entire bladder wall was found. Biopsy revealed "tumor
-forming" eosinophilic cystitis, a rare bladder lesion of unclear cause. An
titoxocariasis treatment was unsuccessful. High-dose corticosteroids failed
. The child's clinical condition and bladder sonographic findings continued
to deteriorate. Treatment with cyclosporin A was given for 8 months, with
a complete clinical, radiologic, and histopathologic cure and no side effec
ts. Two years of follow-up showed a complete recovery.