Eosinophilic cystitis in a 4-year-old boy: Successful long-term treatment with cyclosporin A

Citation
A. Pomeranz et al., Eosinophilic cystitis in a 4-year-old boy: Successful long-term treatment with cyclosporin A, PEDIATRICS, 108(6), 2001, pp. NIL_90-NIL_93
Citations number
31
Categorie Soggetti
Pediatrics,"Medical Research General Topics
Journal title
PEDIATRICS
ISSN journal
00314005 → ACNP
Volume
108
Issue
6
Year of publication
2001
Pages
NIL_90 - NIL_93
Database
ISI
SICI code
0031-4005(200112)108:6<NIL_90:ECIA4B>2.0.ZU;2-2
Abstract
A 4-year-old Jewish boy presented with dysuria, urinary dribbling, increase d urinary frequency, and new onset of diurnal enuresis. An infiltrating sol id mass involving the entire bladder wall was found. Biopsy revealed "tumor -forming" eosinophilic cystitis, a rare bladder lesion of unclear cause. An titoxocariasis treatment was unsuccessful. High-dose corticosteroids failed . The child's clinical condition and bladder sonographic findings continued to deteriorate. Treatment with cyclosporin A was given for 8 months, with a complete clinical, radiologic, and histopathologic cure and no side effec ts. Two years of follow-up showed a complete recovery.