Decreased hippocampal BDNF expression after acute systemic injection of quinpirole

Authors
Fumagalli, F Santero, R Gennarelli, M Racagni, G Riva, MA
Citation
F. Fumagalli et al., Decreased hippocampal BDNF expression after acute systemic injection of quinpirole, NEUROPHARM, 40(7), 2001, pp. 954-957
Citations number
16
Categorie Soggetti
Neurosciences & Behavoir
Journal title
NEUROPHARMACOLOGY
ISSN journal
00283908 → ACNP
Volume
40
Issue
7
Year of publication
2001
Pages
954 - 957
Database
ISI
SICI code
0028-3908(200106)40:7<954:DHBEAA>2.0.ZU;2-8
Abstract
We report that acute quinpirole injection reduces BDNF mRNA levels in the r at hippocampus both at 2 and 6 h after the administration. These results su ggest that the neurotrophin expression may be inhibited by situations invol ving dopaminergic overactivity. (C) 2001 Elsevier Science Ltd. All rights r eserved.