Cigarette smoking is considered the most significant modifiable cause of ad
verse pregnancy outcomes in US women. Despite these well-known adverse effe
cts, many women fail to quit smoking during pregnancy. Socially disadvantag
ed women are at es;especially high risk for continued smoking. Brief office
-based interventions by physicians have shown a doubling of cessation in pr
egnant women, so the potential impact across patient populations is conside
rable. Recommended steps for physician intervention include the following:
asking about smoking, advising smokers to stop, assisting patients in stopp
ing, and arranging followup. Relapse prevention methods using office-based
and social support systems are also important to improve long-term maintena
nce of cessation in women who do quit smoking during pregnancy. Disseminati
on of office-based cessation systems with potential use of pharmacologic th
erapies and in combination with community-based interventions will help inc
rease cessation rates in pregnant smokers. These combined efforts will help
remedy the public health burden of fetal exposure to tobacco.