Background. Lumbar puncture (LP) may be unsuccessful clinically, prompting
image-guided LP by radiologists.
Objective. To investigate the utility of ultrasound (US) in diagnosing the
cause of failed LP and in guiding LP.
Materials and methods. Neonates and infants referred for image-guided LP un
derwent spine US of the thecal sac. When indicated, image-guided LP was per
formed.
Results. Forty-seven evaluations and interventions were performed in 32 pat
ients. All patients were initially evaluated after failed blind LP attempts
. Twenty-three of the initial US studies showed intrathecal and/or epidural
echogenic hematoma, which obliterated the CSF space; 5 showed minimal flui
d, and 4 had normal examinations. LP was deferred or cancelled in 14 cases
based upon initial US findings. Image-guided LP was performed 32 times in 1
9 patients. US guidance was used in 26, fluoroscopy in 3, and fluoroscopy w
ith US assistance in 3. Using US, LP was performed in 9 patients with no vi
sible CSF: 2 samples were sufficient for culture only. Six patients had min
imal CSF US: 4 provided usable CSF samples. Clear CSF space was seen in 11:
all had successful LP.
Conclusions. US can disclose the cause of failed LP, can help determine whe
ther or not to intervene further, and can provide guidance for LP.