Lesions of cloisonne kidney in sheep: report on four cases

This study describes four cases of cloisonne kidney in sheep. These cases w ere seen during examinations of the kidneys of 10.080 sheep from different breeds at slaughterhouse. During this study, 316 (3.13 %) sheep out of 10.0 80 had various kidney abnormalities. Three of cloisonne kidney cases were m acroscopically, the other one was microscopically diagnosed. Grossly, in th ree out of four cases, kidney external surface had diffusely from dark brow n to blackish color. Histopathological examination of hematoxylin-eosin sta ined sections revealed thickening and dark brown pigmentation of the baseme nt membrane of proximal convoluted tubules. Hemosiderin pigmentation was de termined in epithelial cells of proximal convoluted tubules in all cases. S ince the etiology of the condition is unknown, further studies are needed t o be carried out to etiology of cloisonne kidney in sheep and goats.