Cycloisomerization of 1,6-enynes in organoaqueous medium: an efficient andeco-friendly access to furan derivatives. Synthesis of a key intermediate of podophyllotoxin

Authors
Galland, JC Dias, S Savignac, M Genet, JP
Citation
Jc. Galland et al., Cycloisomerization of 1,6-enynes in organoaqueous medium: an efficient andeco-friendly access to furan derivatives. Synthesis of a key intermediate of podophyllotoxin, TETRAHEDRON, 57(24), 2001, pp. 5137-5148
Citations number
64
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
24
Year of publication
2001
Pages
5137 - 5148
Database
ISI
SICI code
0040-4020(20010611)57:24<5137:CO1IOM>2.0.ZU;2-D
Abstract
The first cycloisomerization of enynes catalyzed by Pd(TPPTS)(3) catalyst i n aqueous medium to give functionalized furans is described. This new react ion has been applied to the synthesis of podophyllotoxin analog. (C) 2001 E lsevier Science Ltd. All rights reserved.