Titanium-mediated intramolecular cyclization of tethered propargyl alcoholderivatives. Access to exocyclic bis-allenes and cyclobutene derivatives

Authors
Delas, C Urabe, H Sato, F
Citation
C. Delas et al., Titanium-mediated intramolecular cyclization of tethered propargyl alcoholderivatives. Access to exocyclic bis-allenes and cyclobutene derivatives, TETRAHEDR L, 42(25), 2001, pp. 4147-4150
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
25
Year of publication
2001
Pages
4147 - 4150
Database
ISI
SICI code
0040-4039(20010618)42:25<4147:TICOTP>2.0.ZU;2-H
Abstract
Treatment of tethered bis-propargyl alcohol derivatives with (eta (2)-prope ne)Ti(O-i-Pr)(2) afforded four- and five-membered rings bearing conjugated exocyclic bis-allenes. In the case of six- and seven-membered rings, bicycl ic cyclobutenes were obtained in the same pot most likely via the intermedi ate bis-allenes. (C) 2001 Elsevier Science Ltd. All rights reserved.