The use of liquefied petroleum gas (LPG) as a solvent for yeast reactions

Authors
Johns, MK Smallridge, AJ Trewhella, MA
Citation
Mk. Johns et al., The use of liquefied petroleum gas (LPG) as a solvent for yeast reactions, TETRAHEDR L, 42(25), 2001, pp. 4261-4262
Citations number
7
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
25
Year of publication
2001
Pages
4261 - 4262
Database
ISI
SICI code
0040-4039(20010618)42:25<4261:TUOLPG>2.0.ZU;2-8
Abstract
The yeast mediated reduction of ethyl acetoacetate to ethyl (S)-3-hydroxy b utyrate proceeds with good yield and high enantioselectivity in liquefied p etroleum gas (LPG). It was found that slightly more water (2 ml/g yeast) an d more yeast (1.6 g/mmol substrate) were required to effect complete conver sion than was the case with more conventional organic solvents, such as pet roleum spirit. (C) 2001 Published by Elsevier Science Ltd.