Synthesis of (+)-wikstromol by double alkylation of malic acid

Authors
Sefkow, M
Citation
M. Sefkow, Synthesis of (+)-wikstromol by double alkylation of malic acid, TETRAHEDR-A, 12(7), 2001, pp. 987-989
Citations number
19
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
12
Issue
7
Year of publication
2001
Pages
987 - 989
Database
ISI
SICI code
0957-4166(20010508)12:7<987:SO(BDA>2.0.ZU;2-0
Abstract
The synthesis of (+)-wikstromol in sis steps, based on two stereoselective benzylations of unnatural malic acid derivatives, is presented. The influen ce of the alkyl ester on yield and selectivity in the alkylation of malic a cid esters is examined. (C) 2001 Elsevier Science Ltd. All rights reserved.