Catalyst structure and the enantioselective cyclopropanation of alkenes bycopper complexes of biaryldiimines: the importance of ligand acceleration

Authors
Sanders, CJ Gillespie, KM Scott, P
Citation
Cj. Sanders et al., Catalyst structure and the enantioselective cyclopropanation of alkenes bycopper complexes of biaryldiimines: the importance of ligand acceleration, TETRAHEDR-A, 12(7), 2001, pp. 1055-1061
Citations number
46
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
12
Issue
7
Year of publication
2001
Pages
1055 - 1061
Database
ISI
SICI code
0957-4166(20010508)12:7<1055:CSATEC>2.0.ZU;2-K
Abstract
The use of chiral non-racemic biaryl copper(I) complexes in the enantiosele ctive cyclopropanation of a number of olefins with either ethyl or tert-but yl diazoacetate: is described. Lack of ligand acceleration and the presence of equilibrium amounts of catalytically active uncomplexed Cu(I) ions acco unt for lowered enantioselectivity when using certain ligands. (C) 2001 Els evier Science Ltd. All rights reserved.