In mammals, p53 is crucial for inducing the genes that lead to G1 arrest fo
llowing DNA damage, enabling DNA repair. However, the possibility that such
a system exists in plants has attracted little attention. Even though some
plant cDNA sequences with partial homology to p53 have been reported recen
tly, there has been little analysis of how these molecules might relate to
DNA damage. The lack of investigation into whether a DNA-damage-induced, p5
3-mediated G1-arrest pathway might exist in plants is remarkable given that
plant DNA, like that of all organisms, is continually under the threat of
attack.