We report the first case known to us of a synchronous isolated splenic meta
stasis from colon carcinoma in a 52-year-old woman operated on splenectomy,
left colectomy, and ileal resection. The patient died of diffuse carcinoma
tosis 1 year after the operation. Splenectomy for isolated splenic metastas
is from colon carcinoma is justified, and serum tumor markers are useful to
detect metastases early during the follow-up, as in our report.