Antimicrobial agent resistance in bacterial isolates from patients with diarrhea and urinary tract infection in the Sudan

Antimicrobial sensitivity tests were performed on four-hundred and ninety-s even bacterial isolates from Sudanese patients with diarrhea or urinary tra ct infections. Shigella dysenteriae type 1 and enteropathogenic Escherichia coli showed high resistance rates (percentage of isolates showing antibiot ic resistance) against the commonly-used antimicrobial agents: ampicillin, amoxicillin, chloramphenicol, tetracycline, cotrimoxazole, nalidixic acid, sulfonamide, and neomycin, acid were completely sensitive to ciprofloxacin. Eighteen resistance patterns against nine antimicrobial agents tested were observed in enteric pathogens. Resistance to ampicillin, amoxicillin. tetr acycline, cotrimoxazole, and sulfonamide was the most frequent pattern. The common urinary pathogens, E, coli, Klebsiella pneumoniae, and Proteus mira bilis showed high rates of resistance to ampicillin, amoxicillin, cotrimoxa zole, tetracycline, sulfonamide, trimethoprim, streptomycin, and carbenicil lin. We recommend that physicians seek updated knowledge of the common anti biotic-sensitivity patterns when starting empirical antibiotic therapy in S udanese patients with diarrhea or urinary tract infection.